Research paper on target population-18 yr. olds aging out of Foster Essay

Research paper on target population-18 yr. olds aging out of Foster Care System - Essay Example f individuals risk factors The factors that account for the varied outcomes of aged out individuals are influenced by quality care of foster care facility. Aged out individuals of foster care systems might become innocent victims of physical and emotional changes. Inadequate foster care ends up being more expensive to society because it generates incapable, inefficient suppressed future youth. Application of proactive measures and preventive tools should be taken by the organisations to control their exit out of foster care system. Positive events and quality care experienced by individuals in youth would definitely help them to achieve much more in their life. The strategies should be aimed to improve behavioral outcomes, enhance life satisfaction, and greater level of competence in activities of daily living. Foster care givers are committed to helping the children and young people who are physically, mentally, and/or socially abandoned. Government is responsible to take care of these youths. Local, state and Federal funding operates foster care services (Winder, 2007). When the individual turn 18 years, he/she is out of dependent foster care living system and has to start independent living. Moving into adulthood is important transformation in the span of human life. The individuals at this stage might not be physically and intellectually mature to take right decisions required to drive their future in a proper direction. Aged out individuals of foster care systems might become innocent victims of physical and emotional changes. Many times unfairly treated youth in foster care are saddened and get deeply hurt by surrounding forces. Plight of former foster care young people is of great concern. They might not be that strong to be own their own and stop relying on charity or handouts, whe n they are no longer part of foster care. The factors that account for the varied outcomes of aged out individuals are influenced by quality care of foster care facility.

INVESTIGATION OF HUMAN DISEASE Essay Example | Topics and Well Written Essays - 1000 words

INVESTIGATION OF HUMAN DISEASE - Essay Example Alternatively, a shorted dystrophin gene may be expressed but still different from normal due to an altered molecular weight. Different probes against different parts of the gene, or alternatively gene sequencing, can be exploited to identify the missing parts. Given the almost asymptomatic patient's status, likely due to the young age, no histological features are expected in muscle biopsies. Therefore, a molecular, i.e. immuno-histochemical, analysis will be necessary. Indeed, immunofluorescence (IF) analysis for dystrophin can confirm the genotyping. In physiological conditions, laminin is localized around all muscle fibers and it appears as circles/polygonal shapes in muscle cross-sections, while it is absent in virtually all muscle fibers in diseased individuals (with the notable exception of possible revertant fibers). Given the invasive nature of this procedure, the IF analysis, which requires more tissue to be collected, will be performed as a second option and only in the pr esence of positive genetic tests. On examining the genomic DNA it was found that exon 52 was absent. (b) Will splicing of exon 51 to 53 produce a functional shortened dystrophin? Explain and justify your decision by using an illustration and text (20%). The splicing of exon 51 to 53 does not produce a shortened dystrophin, since the two exons have different codon boundary. The result of the exon 52 deletion, is thus disruption of the genetic code and the premature stop of protein translation. On the contrary, the splicing of exon 51 to 54 would give rise to a shortened but functional form of dystrophin (see diagram below). In the case presented above, the absence of dystrophin expression and the development of DMD is the diagnosis. Scheme of exon boundary extremities in the dystophin region of interest: After genetic counselling the parents choose to seek help from a specialist in gene therapy. (c) If you were the gene therapy specialist what kind of therapy would you suggest for th e boy. Justify your choice. (20%) I would suggest an exon skipping approach with antisense oligonucleotides (AON) aimed to skip exon 53. The loss of the latter in addition to the congenital loss of exon 52 will likely allow to rescue the expression of an almost normal dystrophin, which lacks only two of the repeated motifs that constitute the central body of the protein. Exon skipping has recently been proven an efficient therapeutic approach in large animals (dogs) affected by muscular dystrophy (Yokoda, 2011). PART II (50% total) 1) The picture above shows a family with an inherited disorder. All affected individuals are tall and thin, with long fingers and toes. a) What would a genetic counselor be able to tell an affected individual about the mode of inheritance and the serious complications associated with the disorder (10%) The phenotype of the people in the picture is compatible with the diagnosis of the Marfan. In fact, people with Marfan syndrome tend to be unusually tall, with long, thin fingers. It is inherited as a dominant trait, thus people who have inherited one affected gene from either parent will have Marfan syndrome. This may explain the high penetrance of the disease into a group of individuals, likely members of the same family in the pcture. b) Explain the molecular basis of the condition (15%)

Muhammad Ali: A Biography

Muhammad Ali: A Biography Hard work and persistence are the magical words that lead to success and fame. A very good example is â€Å"Mohamed Ali Clay.† His name was â€Å"Cassius† before being a Muslim. Muhammad Ali built himself by himself until he became the most famous and richest boxer in the entire world. In 1940s, in Louisville, African Americans were separated from Whites. Black people were only permitted to sit in back rows of movie theatres and buses. Moreover, black children were separated from white children and they could not go to school together. Moreover, some of the restaurants would not allow blacks in. This system was called â€Å"segregation.† Louisville had two African American neighborhoods, east end (the California area), and west end (where the Clays lived). The clays were very poor. Their car was ten years old, their house always needed painting, the porch sagged, and whenever it rained, water entered the house from the roof. Cassius Marcellus, who was born on the 17th of January 1942, and Rudy his brother, were sharing the same pants and the same shirts. After a while, the Clays gave them a new shirt and new pants. Odessa Clay their mother, used to work at houses when her sons were young, and earned four dollars a day. She was very religious. Every Sunday sh e attended with her two sons Mount Zion Baptist church, where Cassius used to sing in the choir. Odessa taught Cassius to treat people kindly (Muhammed Ali, by Arlene Schhulmain, published 2005). In 1954, when Cassius was twelve, his father bought him a new bicycle for Christmas. A new bicycle was an enormous thing for them, because they were a poor family. One day, Cassius went to a show with his friend on his new bicycle. After the show was over, Cassius could not find his bike and he went to a police officer, who tried to help him but could not. Later on, Cassius found the thief and he hit him and then went to the officer and told him that he found the thief and he had beaten him up. That day was the birth of the champion! The police officer took him to a place for boxing, where he could learn boxing and told him â€Å"If you want to learn how to hit, learn boxing.† Joe Martin, who was a boxing coach, helped him to join his club ((Muhammed Ali, by Arlene Schhulmain, published 2005). One day Cassius saw his coach on a television show called â€Å"Tomorrows Champions†. When Cassius saw this show, he went to Joes gym and started to learn boxing. Cassius was very thin and weighed only eighty nine pounds. He did not have muscles, however he learned quickly because he had fast punches and fast feet and this was considered very good for a beginner. After six months of training at Martins gym, Martin finally told him that he would appear on the television show and he would fight a boy for a round for two minutes. When Cassius went, he won the match and it was the first success for him. Cassius was now on the way to becoming a champion. When he went home, he would hit the bullies who picked on him and his family, until they ran home with bloody noses. The people in the neighborhood called him the â€Å"king.† In 1995, Cassius was going to Duvalle High School to travel for competitions and learn more boxing. By 1960, he won six Kentucky Golden Gloves championships and two National Amateur Athletic Union (AAL) titles. At the time when Cassius was eighteen, he earned one hundred out of one hundred and eight Amateur Championships (The Greates t Muhammed Ali, by Walter Dean Myers, published 1996). Cassius then started to think about making a name for himself. He was thinking of becoming a pro player, but Martin convinced him to continue and attend the Olympics in order to become a pro player. In 1960, he won his first Olympics. This was in Rome and all people would shake hands with him. He felt very happy signing autographs for his fans. When Cassius went to Louisville, people were waiting for him and cheered for him, but in the United States he still didnt have all his rights. Cassius decided to turn pro and he went to find a sponsor. He chose the Louisville group, which was trying to find him a coach to teach him how to box like a professional. Cassius goals were to buy a new house for his parents and buy a new Cadillac for himself. He found a coach called Dundee, who trained him very well. After that, Cassius moved to Miami, Florida were Dundee trained his fighters. He lived in a small room with dirty windows and unpainted walls. In 1960, he had the first pro match with Tun ney Hunsaker. Everyone knew that Clay would win the match, and he really did win and received two thousand dollars (The Greatest Muhammed Ali, by Walter Dean Myers, published 1996). Cassius was the first one to enter the gym and the last one to leave. Many reporters and newspapers liked him for his funny jokes and his interesting quotes. In 1962, Clay faced a big challenge. There was a popular pro player, whose name was Archie Moore and who was forty nine years old. Clay was only twenty years old then. They played a match that ended for Clays victory. He became more popular and all pro fighters were curious to fight him. In 1963, Clay was to fight Doug Jones, and that match ended also for Clays victory but he won it in ten rounds! Clay had the biggest match of all held on 1964. He fought a champion who was 220 pounds of muscles! His name was Sonny Liston. Before entering the match, Clay was scared to death and doctors expected him to give up in the match. When he entered, he preformed very well in that he cut Liston, and it was the first time for Liston to be cut in a match. Liston had to take a medication to continue the match and the medication ended up on his gloves, so when Liston punched Clay in the face, Clay couldnt see because it was hurtinzg him so much. He washed his face with water and then continued the match and won. This made Clay more famous (www.answers.com/topic/muhammad_ali_boxer) and (The greatest Muhammed Ali, by Arlene Schulman, published 2005). At that time, Clay was attending the Nation of Islam group meetings secretly. He didnt want anyone to know because he could be sent out of boxing. After the match with Liston, he announced that he is a Muslim and he changed his name to â€Å"Muhammed Ali.† After that, he began to address the members of the Islam group and gave speeches for them. In 1964, Ali married Sonj Roi , who refused to wear Muslim dress, smoked cigarettes and went to nightclubs. He soon divorced her, and then married in 1967 a Muslim woman called Belinda. Ten years later â€Å"Maryum Ali† was born. In 1972, Ali opened a training camp at Deer Lake. Later in 1978, he went to the great fight with Leon Spinks, who won against Ali. After that, Ali demanded a re-match, trained for it and won. In 1979, Ali had two more girls named â€Å"Laila and Hana.† Ali was very proud of them (www.novaonline.nvc.edu/eli/evans/his135/events/ali98.htm). One day, Ali decided to retire, but this did not last long because he loved boxing. He came back to the ring stronger than ever. Unfortunately, after some time, he was beaten up by Larry Holmes, who erased Alis hopes of coming back to boxing. From that day, he insisted on retiring and became a very good coach, who trained children. You hear a lot now about his daughter, Laila Ali, who is following in her fathers footsteps (www.novaonline.nvc.edu/eli/evans/his135/events/ali98.htm). Obviously, Muhammed Ali Clays life story is very inspirational. It shows how ambition and hard work would take one to new worlds; worlds of success, wealth, achievement and fame. His strength, tolerance and persistence will always be a guide for many.

Gender Issues of Mesopotamia Essay -- Gilgamesh Gender Female Rights E

Gender Issues of Mesopotamia  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚   Throughout the history of our society, women have gained a certain respect and certain rights over time. Such simple aspects of life such as getting a job, voting, and even choosing who they would like to marry are things that women have fought for, for many years. At one point, these were all things that women in America and parts of Europe had no right to. Men as a whole had suppressed women and taken control of the society. Despite mass oppression in history, women have risen in society and now posses these natural rights.   Ã‚  Ã‚  Ã‚  Ã‚  Back in the days of Mesopotamia, things were quite different. Women were respected for who they were and did not have to fight to gain the rights they had. Hammurabi’s Code contained laws, which respected the rights of women. Society in general was formed around this sort of sexual equality. Many of the codes within Hammurabi’s Code favor the men of the society, though many of them spell out certain rights for the lives of the women. Certain laws lie within Hammurabi’s code in order to solve problems of the society. It spells out the punishment for certain acts eliminating any further complications. Code 136 for example, explains what is to happen to a women who’s husband runs off; â€Å"If any one leave his house, run away, and then his wife go to another house, if then he return, and wishes to take his wife back: because he fled from his home and ran away, the wife of this runaway shall not retur...

Pencils Are Better Than Pens – Debate

Pencils are better than Pens Ladies and gentlemen, When you go to war you want to be prepared with the right weapons. Having the wrong ones can limit you success and impair your skills. Isn’t this the same case for writing a paper? When you sit down to write a paper you want to make your ideas flow, to be able to erase false ones, and stay focused; pencils enable you to do all of those things more effectively than pens. Pencils have erasers to fix all your mistakes, they’re 100% organic, and contrary to pens, which can be very messy, pencils are neat and long lasting.When you are writing, you make mistakes all the time. You write words messily, you spell them wrong, and you mix up the order of what you are trying to say. If you are writing with a pen you have to scribble out all of those misspelled words or draw arrows to where you want things to be. When you’re done, it looks like a paper in disarray. If you write with a pencil you don’t have to do any of that. You can erase all of your misspelled words, and neatly move sentences to where ever you want. When you’re finished your paper looks faultless.It has no messy scribbles or long confusing arrows, everything is precisely how you want it to be. Of course scientists have created an erasable pen, but it doesn’t work as well as pencils. Erasable pens can erase, but they normally leave streaks or smudges on the page. You also can’t just use any eraser on it, it has to be a special eraser that costs more than a regular pencil eraser. Pencils are much more affective at erasing and keeping papers mess free. Secondly, pencils are 100 percent organic. They are made up of cedar, graphite, and metal.Which are all organic substances. Pens are made up of plastic and ink. Ink is made up of oil, which is harmful to the earth. Plastic is not organic, and pollutes the environment. Also if you break a pen in half, it is permanently broken, and becomes incredibly messy. Once th ey are broken they end up getting thrown away, and produce more trash. When a pencil is broken in half. All you have to do is sharpen it, and you have two pencils! This then reduces the amount of wasted materials. With that in mind, pens are much messier than pencils. Pencils can’t write n you or other objects besides paper. But pens on the other hand can write on almost any surface. Even when you write, you can smudge it all over your page when its not dry, it gets all over your hands, and it’s very hard to get off of your skin. Once your skin absorbs the ink it can give you ink poisoning. But pencils can’t poison you, or do anything permanently harmful to you, and they are mess free. Lastly, pencils are a very useful and long lasting utensil. According to Dixon Ticonderoga Pencil Company, pencils can draw a line 35 miles long.And according to bicworld. com pens can draw a line 1. 24 miles long. Using one pencil is the equivalent to using 28 pens. One organic p encil eliminates much more waste than 28 pens do. In conclusion, pencils are the prime utensil for writing a paper. Pencils have erasers to erase all your mistakes. They are 100 percent organic, and unlike pens they are neat and long lasting. You don't want to impair your skills nor limit your success, so when you sit down to write a paper, remember to use the better writing utensil, the pencil. Thank you.

Confirmation: Early Christian Community Essay

For people in the Early Christian Community who wanted to commit themselves as followers of Christ they first needed to receive the sacraments of initiation. Initiation into the Church took place in a single ceremony, which normally unfolded during the Easter Vigil service. In the early church, the three Sacraments of initiation—Baptism, Confirmation, and Eucharist—were celebrated in the same ceremony by adult converts. Although there was no clear emergence of Confirmation as a separate sacrament until after the third century, the elements of the Sacrament of Confirmation can be recognized in the Sacrament of Baptism in the early writing of the bible. After a long period of instruction that sometimes lasted as long as three years, each person was baptized, confirmed and also received the Eucharist. They were then brought before the Bishop where he laid his hands on each of their heads and prayed that they might receive the gift of the Holy Spirit and become responsible Christians living through Christ to fulfill his life long mission. At some point in the early Christian Community, the sacraments of initiation, baptism and confirmation, became primarily a sacrament for infants. Their baptism would allow them to become a member of the church and then confirmation would happen right after this, which was when the bishop would confirm or acknowledge this commitment. Eventually, however in the early 1900’s confirmation became a sacrament associated not with infants but with older youths. Where each child can consciously make the decision to strengthen the bond with god and accept the reasonability to the church and to others as well.